What’s the New Multiple Sclerosis Treatment? Emerging therapies are offering hope to millions of people living with MS. Among these developments is Stem Cell Therapy, which continues to show promise in halting disease progression and even repairing nerve damage. We look at the latest MS Treatments, including Stem Cell Therapy and how they all compare.
Aside from MS, if you’re curios about how Stem Cells can help with other conditions, our article on What conditions can Stem Cell Therapy treat might be useful!
If you’re considering Stem Cell Therapy, our team can guide you in deciding if it’s the right fit, help you choose the best clinic & region, and even assist you in securing some great discounts! Fill in our form here to set up a conversation.
Breakthroughs in New Multiple Sclerosis Treatments
The landscape of MS treatments is evolving with exciting new approaches. Here’s a quick overview, we’ve simplified all the explanations to help:
- Approved drugs:
– Siponimod (Mayzent): Helps reduce how often MS symptoms flare up and slows down disability progression in people with relapsing MS by calming down overactive parts of the immune system.
– Briumvi (ublituximab): A treatment that lowers inflammation in the body by targeting and removing certain immune cells (B cells) that contribute to MS getting worse.
– Ocrevus Zunovo: A new version of Ocrevus that can be injected under the skin just twice a year. It’s more convenient than the traditional IV treatments and works to slow down both relapsing and progressive MS and was just approved in 2024. - Experimental Drugs:
– These focus on repairing the damaged coating (myelin) around nerves. By fixing this “protective shield,” these treatments may actually reverse some MS symptoms.
– Tolebrutinib: Still being tested, this medication shows promise for people with a specific type of MS (non-relapsing secondary progressive MS). It targets cells in the brain to help stop the disease from progressing.
– Fenebrutinib: Currently in Phase III clinical trials, this BTK inhibitor is being evaluated for both relapsing MS and primary progressive MS. It works by targeting immune cells responsible for inflammation and disease progression. - Technology-Based Treatments:
– Wearable Devices: Track and monitor symptoms like fatigue and mobility in real-time, helping both patients and doctors adjust treatment plans more effectively. - Stem Cell Therapy
– Stem cell treatments, particularly hematopoietic stem cell transplants (HSCT), are being explored as a way to “reset” the immune system and reduce inflammation. Mesenchymal stem cells (MSCs) are also gaining attention for their potential to repair nerve damage and promote remyelination.
Multiple Sclerosis can be frustrating and overwhelming to treat. We’re not here to hype miracle cures. Our goal is to help you decide for yourself if it’s worth exploring, risks involved & treatment prices around the world.
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What’s the Best New MS Treatment?
Treatment | How It Works | Benefits | Challenges | Approved |
| Stem Cell Therapy | Uses Hematopoietic Stem Cells (HSCs) to reset the immune system and Mesenchymal Stem Cells (MSCs) to repair myelin. | Halts progression and repairs nerve damage. | Expensive, limited long-term data, variable outcomes. | No |
| Siponimod (Mayzent) | Targets specific immune pathways to reduce attacks and slow disability in relapsing MS. | Reduces relapse frequency and progression. | Requires ongoing use, potential side effects. | Yes |
Briumvi (Ublituximab) | Monoclonal antibody that depletes B cells to reduce inflammation and slow disease progression. | Effective at reducing inflammation. | Administered via infusion; immune suppression risks. | Yes |
Ocrevus Zunovo | Subcutaneous form of Ocrevus, administered twice a year, targeting B cells to slow MS progression. | Convenient injections; slows both relapsing and progressive MS. | Potential immune suppression, relatively new. | Yes |
| Experimental Drugs | Focus on remyelination to repair myelin and potentially reverse symptoms. | Potential to repair nerve damage. | Still in trials; long-term efficacy unknown. | No |
| Tolebrutinib | A BTK inhibitor targeting inflammation in non-relapsing secondary progressive MS. | Promising for nrSPMS. | Still under investigation, possible side effects. | No |
| Infusion Therapy | Administers drugs like Ocrevus and Tysabri directly into the bloodstream to modulate immune activity. | Reduces relapses and slows disease progression. | Requires regular infusions; immune suppression risks. | Yes |
| Tysabri (Natalizumab) | Blocks immune cells from crossing the blood-brain barrier, reducing inflammation. | Effective for relapsing MS | Risk of serious infections (e.g., PML). | Yes |
Monomethyl fumarate (Bafiertam) | Reduces inflammation and protects against oxidative stress. | Oral medication; fewer side effects than other MS drugs. | May not be effective for all types of MS | Yes |
Fenebrutinib | Targets BTK to modulate immune response and inflammation. | Potentially effective for progressive forms of MS. | In clinical trials; side effects unknown. | No |
How Stem Cell Therapy for Multiple Sclerosis Works
Stem cell therapy takes a unique approach to treating multiple sclerosis by addressing both the immune system and nerve repair:
- Hematopoietic Stem Cells (HSCs): These stem cells “reset” the immune system by eliminating immune cells that attack healthy tissue, replacing them with new, healthy ones. This can stop the progression of MS.
- Mesenchymal Stem Cells (MSCs): These stem cells focus on repairing damage. They promote the regeneration of myelin, reduce inflammation, and support the recovery of nerves affected by MS.
Unlike conventional treatments, which primarily focus on managing symptoms or slowing the disease, stem cell therapy aims to address the root causes. While it doesn’t guarantee a cure, it offers hope for halting progression and even reversing some damage in certain cases.
If you want to understand how stem cell therapy works in general, check out our article on how Stem Cell Therapy works.
Latest Research on Stem Cell Therapy for MS: What You Need to Know
The research looks pretty good, but let’s be clear—this isn’t a one-size-fits-all solution.
- HSC Transplants (HSCT): These are making waves in halting MS progression, especially for patients with relapsing-remitting MS. A study spoken about here shows that over 60% of patients saw stable or improved symptoms after the treatment.
- A super interesting review completed in January 2025 shows that AHSCT can help people with aggressive relapsing MS who haven’t responded to other treatments by resetting their immune system, often leading to long-term remission. It also goes in depth on side effects and overall safety too.
- MSCs for Repair: MSCs have shown promise in reducing inflammation and repairing nerve damage, but we still need more long-term data to confirm their full impact. Early studies highlight that while results are positive, it’s not a magic fix.
To go into more depth on current trials and studies done, this article might be helpful.
Looking into Stem Cell clinics for Multiple Sclerosis?
Browse verified stem cell clinics in Colombia, Japan and more that we’ve already personally vetted.
Browse Verified Stem Cell ClinicsDoes insurance cover stem cell therapy for MS?
In most cases, insurance does not cover stem cell therapy for MS because it is considered experimental.
Who is eligible for stem cell transplant for MS?
Eligibility for HSCT or MSC therapy typically depends on:
- Type of MS: HSCT is most effective for relapsing-remitting MS. Progressive MS patients may qualify but with varying outcomes.
- Disease Activity: Active inflammation and disease progression despite conventional treatments increase eligibility.
- Health Status: Candidates must be healthy enough to undergo chemotherapy (used in HSCT to reset the immune system).
- Age Restrictions: While there’s no strict age limit, younger patients often respond better to treatment.
Key Benefits of Stem Cell Therapy for Treating MS
Stem cell therapy offers some exciting possibilities:
- Resets the Immune System: HSCs can stop the immune system from attacking your nerves.
- Tissue Repair: MSCs work on repairing myelin, which could improve MS symptoms over time.
- Less Invasive: Compared to other treatment options, this approach is relatively low on invasiveness.
Real Risks and Challenges of Stem Cell Therapy for Multiple Sclerosis
While stem cell therapy offers exciting possibilities for treating MS, it comes with unique challenges and risks:
- Cost: Treatments typically exceed $20,000 per session, and insurance rarely covers experimental therapies like stem cell treatment for MS. This makes it a significant financial investment for many patients.
- Limited Long-Term Data for MS: Most studies on stem cell therapy for MS track patients for just a few years. While early results show promise, we lack robust long-term evidence to confirm sustained benefits or potential risks over time.
- Varied Outcomes Among MS Patients: Success rates for stem cell therapy in MS patients can vary widely. Some individuals experience halted progression or symptom improvement, while others see minimal changes. This unpredictability makes it challenging to identify who is most likely to benefit.
- High-Dose Chemotherapy Risks (Specific to HSC Transplants): Hematopoietic stem cell transplants (HSCT) require high-dose chemotherapy to suppress the immune system before the transplant. This process carries serious risks, such as severe immune suppression, increased susceptibility to infections, and prolonged recovery times.
Practical Advice for Patients Suffering with MS
Lifestyle Considerations:
Diet: Adopt an anti-inflammatory diet rich in omega-3s and antioxidants.
Exercise: Focus on low-impact activities like swimming or yoga to maintain mobility.
Avoid Stress: Stress can exacerbate MS symptoms; mindfulness practices can help.
Best Stem Cell Therapy clinics for Multiple Sclerosis
We don’t let any clinic just sign up or pay to be listed.
We speak to every clinic directly and review their medical team, the treatments they offer, how their stem cells are sourced and how they follow up with patients after treatment.
We also review licensing documents to confirm they meet the legal and medical standards of the country they operate in. For example, whether cells are processed in a GMP-certified facility or if they provide documentation on stem cell quality.
Clinics must also agree to let us collect and publish independent patient reviews. Both positive and negative.
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Top Stem Cell Therapy Clinics in India for Multiple Sclerosis
Plexus is a leading center for neurological rehabilitation and stem cell therapy, helping patients with stroke, Parkinson’s, Autism, and more. Their facility is India’s first ISO-certified stem cell research center.
View Full ProfileTop Stem Cell Therapy Clinics in Colombia for Multiple Sclerosis
Alevy specializes in stem cell and exosome therapy, using umbilical cord-derived MSCs to treat a wide variety of conditions, from Diabetes, Multiple Sclerosis to Osteoarthritis & Orthopaedic injuries. Their medical team brings over 15 years of experience in pain management, tissue regeneration, and immune system modulation. With three world-class clinics in Medellín, Bogotá, and Pereira, you have options on where you want treatment!
View Full Profile
Kyron Stem Cells is a Stem Cell Therapy clinic that focuses on a variety of treatments, including joint pain, chronic fatigue, autoimmune issues, and overall wellness. The clinic is led by Dr. Carlos Rojas, who has been working with stem cells since 1991 and has over a decade of experience in functional and hormone-based medicine. He is known for creating treatment plans that are genuinely personalized, based on each patient’s biology and lab results.
View Full ProfileIs Stem Cell Therapy the best new Multiple Sclerosis Treatment?
Stem cell therapy offers a different option for MS patients, particularly those with relapsing-remitting MS who are seeking a treatment that could halt progression. Hematopoietic stem cell transplants (HSCs) have shown significant promise, while mesenchymal stem cells (MSCs) are still being researched for nerve repair.
While it may not be suitable for everyone, especially due to the high costs and variability of results, it represents a new frontier in MS treatment.
You’ve read about newly approved drugs, infusion therapy and other experimental approaches, if you’ve tried it all and nothing has worked, you might want to look into Stem Cell Therapy. But remember, whilst results have been positive, it is early days and results do vary from person to person.
But, it’s looking like Stem Cell Therapy is or will be a new treatment for Multiple Sclerosis!
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The most notable new MS treatments in 2024 include:
Stem Cell Therapy: Emerging as a breakthrough for patients with severe MS, particularly Hematopoietic Stem Cell Transplants (HSCT), which reset the immune system and halt disease progression. Mesenchymal Stem Cells (MSCs) show promise for repairing nerve damage and improving mobility, offering hope for long-term recovery.
Siponimod (Mayzent): A drug designed for relapsing MS that reduces the frequency of attacks, helping patients manage symptoms more effectively and maintain their quality of life.
Briumvi (ublituximab): A monoclonal antibody therapy aimed at slowing MS progression by targeting and reducing inflammation, giving patients a chance to delay disease advancement.
People with MS should avoid:
Alcohol: Excessive consumption may exacerbate symptoms like fatigue and balance issues.
Caffeinated Beverages: While not harmful in moderation, too much caffeine can lead to dehydration and worsen bladder symptoms.
Sugary & Energy Drinks: These can contribute to inflammation and energy crashes, making MS symptoms harder to manage.
Processed and Fried Meats: Processed meats (like bacon, sausages, and deli meats) and fried meats are high in unhealthy fats, preservatives, and compounds that may promote inflammation, potentially exacerbating MS symptoms.
Meat and Chicken Debate: There is ongoing debate in the MS community about whether meat and chicken contribute to internal inflammation. While some studies suggest that processed or conventionally raised meat may promote inflammation, others highlight that lean, unprocessed meats and poultry can be part of a balanced diet. As a precaution, some recommend reducing or eliminating meat to manage inflammation.
Thanks to advancements in treatment, the life expectancy of people with MS is approaching that of the general population. On average, MS may reduce life expectancy by about 5-10 years. However, early diagnosis, effective management, and lifestyle adjustments can significantly improve quality of life and longevity.
The best stem cell treatment for MS is Hematopoietic Stem Cell Transplantation (HSCT), particularly for patients with relapsing-remitting MS. Studies show HSCT can halt disease progression for many patients, with some achieving long-term remission. Clinics offering HSCT with a strong track record include those in Mexico, Russia, and the U.S.
For nerve repair and myelin regeneration, Mesenchymal Stem Cell (MSC) therapy is gaining traction, though it is still in the experimental stage. Leading clinics in Europe and Asia are pioneering MSC treatments.
Stem cells can’t fully cure autoimmune diseases yet, but they may help by reducing inflammation and repairing damaged tissue. Some treatments, like HSCT for MS or MSCs for lupus and Crohn’s are showing good signs of promise! If you want to see the most recent research on these treatments, check out our research section – we’ve collated tons of the most recent research in one place for you.
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